Research Group A01: Elucidation of the molecular basis of Biological Clusters and their relationship to cellular functions
For the target supramolecular complexes, we comprehensively elucidate the molecular basis of their basic units and the formation mechanisms and acquired characteristics of the supramolecular complexes.
Research Group A02: Visualization of Biological Clusters and their molecular dynamics
Using advanced high-precision imaging analysis, we observe supramolecular complexes within cells and elucidate their characteristics and molecular dynamics control.
Research Group A03: Formation and characterization of Biological Clusters by physical and mathematical analysis
By measuring physical quantities related to supramolecular complexes and conducting parallel mathematical theoretical analyses, we elucidate the functional characteristics of clusters and the elements involved in their formation.
Member
A01: Elucidation of the molecular basis of Biological Clusters and their relationship to cellular functions
Formation mechanism of functional kinetochores via Biological Clusters
Role of SMC complex clusters in chromosome organization
Formation and characteristics of Biological Clusters at centromeres
Formation mechanism of centrosomes via Biological Clusters
A02: Visualization of Biological Clusters and their molecular dynamics
Structural and dynamic analysis of Biological Clusters using cryo-TEM and SEM
Establishment of ultimate spatiotemporal correlation spectroscopy for analyzing Biological Clusters
A03: Formation and characterization of Biological Clusters by physical and mathematical analysis
Elucidation of biomolecular cluster formation and supramolecular structural transitions in cell-sized spaces
Theoretical study for the states of biological clusters based on the characteristics of molecular fields