Research Organization
Organization
Research Group
- Research Group A01: Elucidation of the molecular basis of Biological Clusters and their relationship to cellular functions
- For the target supramolecular complexes, we comprehensively elucidate the molecular basis of their basic units and the formation mechanisms and acquired characteristics of the supramolecular complexes.
- Research Group A02: Visualization of Biological Clusters and their molecular dynamics
- Using advanced high-precision imaging analysis, we observe supramolecular complexes within cells and elucidate their characteristics and molecular dynamics control.
- Research Group A03: Formation and characterization of Biological Clusters by physical and mathematical analysis
- By measuring physical quantities related to supramolecular complexes and conducting parallel mathematical theoretical analyses, we elucidate the functional characteristics of clusters and the elements involved in their formation.
Member
A01: Elucidation of the molecular basis of Biological Clusters and their relationship to cellular functions
Formation mechanism of functional kinetochores via Biological Clusters
Professor, Graduate School of Frontier Biosciences, Osaka University
Role of SMC complex clusters in chromosome organization
Associate Professor, Department of Chromosome Science, National Institute of Genetics
Formation and characteristics of Biological Clusters at centromeres
Division Head, Cancer Institute, Japanese Foundation for Cancer Research
Formation mechanism of centrosomes via Biological Clusters
Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo
A02: Visualization of Biological Clusters and their molecular dynamics
Structural and dynamic analysis of Biological Clusters using cryo-TEM and SEM
Professor, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi
Professor, Institute for Protein Research, Osaka University
Assistant Professor, Graduate School of Medical and Dental Sciences, Kagoshima University
Establishment of ultimate spatiotemporal correlation spectroscopy for analyzing Biological Clusters
Senior Lecturer, Faculty of Advanced Life Science, Hokkaido University
Researcher, Department of Experimental Pathology, Cancer Institute, Japanese Foundation for Cancer Research
Specially Appointed Researcher, Department of Experimental Pathology, Cancer Institute, Japanese Foundation for Cancer Research / Visiting Faculty, Graduate School of Frontier Biosciences, Osaka University
A03: Formation and characterization of Biological Clusters by physical and mathematical analysis
Elucidation of biomolecular cluster formation and supramolecular structural transitions in cell-sized spaces
Associate Professor, Department of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo
Senior Scientist, Japan Agency for Marine-Earth Science and Technology
Theoretical study for the states of biological clusters based on the characteristics of molecular fields
Associate Professor, School of Science, Yokohama City University
Specially Appointed Associate Professor, School of Science, Yokohama City University
Publicly Offered Research（FY2024-2028）
A01
Structural basis of a huge machinery for collagen secretion
Satoshi Watanabe
Associate Professor, Medical Institute of Bioregulation, Kyushu University
Dynamics of peri-centrosomal giga-clusters in response to extracellular stimuli
Koji Ikegami
Professor, Graduate School of Biomedical and Health Sciences ,Hiroshima University
Elucidation of immune mechanisms and their regulation via biological clusters
Umeharu Ohto
Professor, Graduate School of Frontier Sciences, University of Tokyo
Coordinated assembly of the mitotic spindle by three microtubule-nucleation pathways
Tomomi Kiyomitsu
Assistant Professor, Cell Division Dynamics Unit, OIST
Architecture, Regulation and Performance of Mitotic Stress Memory
Franz Meitinger
Assistant Professor, Okinawa Institute of Science and Technology
Understanding the Orchestration and Higher-Order Structure of Actin Cytoskeleton Factors through Optical Control
Hideaki Matsubayashi
Assistant Professor, FRIS, Tohoku University
The assembly and dynamics of supermolecular complexes that govern plasma membrane function.
Yoshihisa Oda
Professor, Graduate School of Science, Nagoya University
Analysis of the Golgi formed by clusters of small units which includes enzyme clusters
Akihiro Harada
Professor, Grad. Sch. Med., Dept. Cell Biol., The University of Osaka
Reconstitution and dissection of biological clusters that underlie mitotic chromosomes
Keishi Shintomi
Senior Scientist, Pioneering Research Institute, RIKEN
A02
Cryogenic electron tomography of the higher-order assembly of synapse organizers
Shuya Fukai
Professor, Graduate School of Science, Kyoto University
Working principle of supramolecular complexes controlling neurotransmitter release
Hirokazu Sakamoto
Assistant Professor, Department of Pharmacology, Graduate School of Medicine, The University of Tokyo
Biological Clusters at the Nuclear Pore–Chromatin Interface: visualizing molecular regulatory dynamics
Richard Wong
Professor, WPI Nano Life Science Institute, Kanazawa University
Visualize the local state of microtubules that can regulate the affinity and position of biological clusters
Tomohiro Shima
Assistant Professor, Department of Biological Sciences, The University of Tokyo
The mechanism of plant twisting caused by mutations in microtubule biological cluster
Tsuyoshi Imasaki
Division of Structural Medicine and Anatomy Lecturer, Kobe University
Analytical method for solidification of liquid-liquid phase separates
Motonari Uesugi
Professor, Institute for Chemical Research, Kyoto University
A03
Molecular simulation study of cytoskeleton growth coupled with phase separation
Shoji Takada
Professor, Graduate School of Science, Kyoto University
Mechanics of biological cluster
Daisuke Mizuno
Physics Professor, Kyushu University